Nonceliac wheat sensitivity: A new clinical entity

About 20 years ago I completed an internship in a small company specializing in the formulation of gluten-free bakery products for patients with celiac disease. At the time, celiac disease was pretty much unknown from the general population. Few people were affected, and few products existed to replace the staples of general diets that the affected individuals needed to avoid to remain symptom-free, such as bread, pasta, cookies, cakes, breakfast cereals, and all products containing (or made from) wheat, rye and barley.

Today, it is hard to escape discussions of intolerance to gluten. What happened? Did the frequency of the celiac disease suddenly skyrocket? Apart from an increased awareness of celiac disease per se, clinicians are starting to recognize the existence of another type of food intolerance triggered by wheat, namely nonceliac wheat sensitivity. Continue reading