Ketogenic diet: variations on a classic (including the Atkins diet)

Ketogenic diets pie

Ketogenic diets pie (Photo credit: Wikipedia)

The ketogenic diet is a high fat, low-carbohydrate and adequate protein diet, which was originally developed to treat epileptic individuals (see my previous posts about the use of the diet for epilepsy and the mechanisms of action of the diet). The diet produces remarkable  results on subjects suffering from intractable seizures but also revealed quite useful for a variety of other conditions, such as narcolepsy and autism and shows promises for the treatment of Alzheimer’s disease, Parkinson, Amyotrophic Lateral Sclerosis, Multiple Sclerosis, migraine headache, depression and type-2 diabetes (see my post on the use of ketogenic diet beyond epilepsy).

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The ketogenic diet: beyond epilepsy

The ketogenic diet was developed in the 1920′ as a treatment for intractable epilepsy. In more than 20% of individuals, the diet offers complete remission from seizures, and it decreases by 75% the frequency of attacks in more than half of the patients (see my previous post on the use of the ketogenic diet for epilepsy).

English: PET scan of a human brain with Alzhei...

English: PET scan of a human brain with Alzheimer’s disease (Photo credit: Wikipedia)

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How does the ketogenic diet work?

English: of beta-hydroxybutyric acid. Created ...

English: of beta-hydroxybutyric acid. Created using ACD/ChemSketch 10.0, and vim. (Photo credit: Wikipedia)

The ketogenic diet is a high fat, adequate protein, low carbohydrate diet, which has been used for almost a century to treat cases of epilepsy resisting to anticonvulsant medications (see my previous post for more details). However, although its efficiency is now widely accepted, the exact mechanisms by which it operates are still not completely understood. Continue reading